A large effective population size for established within-host influenza virus infection
نویسندگان
چکیده
منابع مشابه
Bacillus subtilis as a Host for Recombinant Hemagglutinin Production of the Influenza A (H5N1) Virus
Abstract Background and Aims: Influenza A(H5N1) viruses circulating in animals might evolve and acquire the ability to spread from human to human and thus start a pandemic. Hemagglutinin (HA) has been shown to play a major role in binding of influenza virus to its target cell and the main neutralizing antibody responses elicit against this region. Recent studies have shown that...
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1 Institut Pasteur, Unité de Défense Innée et Inflammation, Paris, France 4 2 INSERM U874, Paris, France 5 3 Institut Pasteur, Unité de Génétique Moléculaire des Virus ARN, Paris, France 6 4 School of public Health The University of Hong Kong, HongKong SAR, China 7 5 INSERM UMR-S1155, Paris, France 8 6 The HKU-Pasteur Research Pole, School of Public Health The University of Hong Kong, 9 HongKon...
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Influenza A viruses (IAVs) are contagious pathogens responsible for severe respiratory infection in humans and animals worldwide. Upon detection of IAV infection, host immune system aims to defend against and clear the viral infection. Innate immune system is comprised of physical barriers (mucus and collectins), various phagocytic cells, group of cytokines, interferons (IFNs), and IFN-stimulat...
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ژورنال
عنوان ژورنال: eLife
سال: 2020
ISSN: 2050-084X
DOI: 10.7554/elife.56915